CryoSPARC™, developed by Structura Biotechnology Inc., is a specialized platform for automated reconstruction of target and target-ligand structures from single particle cryo-EM data.
CryoSPARC powers high-throughput cryo-EM in drug discovery by combining proprietary computer vision and machine learning algorithms with robust workflows to enable recovery of the highest quality structures, especially for valuable targets like membrane proteins.
With this investment, leadXpro complements its unique expertise of construct design, membrane protein expression and purification expert knowledge, grid freezing and cryo-EM measurement* with professional data analysis for high resolution cryo-electron microscopy. Structural details inform about the interaction of the drug target protein with small molecule or biotherapeutic ligands to facilitate the discovery, optimization and characterization of potential medicines.
*in collaboration with C-CINA of the University of Basel